(A) Kaplan-Meier analysis of breast cancer specific survival based on αB-crystallin expression. 10-year breast cancer specific survival was 64% for αB-crystallin-positive cases (n = 359, number of events = 133) versus 75% for αB-crystallin-negative cases (n = 2870, number of events = 809), P < 0.0001 by log-rank test. (B) Kaplan-Meier analysis of distant relapse free survival based on αB-crystallin expression. 10-year distant relapse free survival was 62% for αB-crystallin-positive cases (n = 359, # of events = 139) versus 70% for αB-crystallin-negative cases (n = 2876, # of events = 915), P = 0.0016 by log-rank test.