Study	Reason for exclusion
Alport 2012	Comparison of different peripherally-inserted central venous catheters in non-coagulopathic patients
Amarapurkar 2014	Non-randomised observational study
Bartelmaos 2013	Comparison of quarantine, methylene blue and solvent/detergent plasmas in liver transplant recipients
Carino 2009	Non-randomised observational study
Corash 2006	Comparison of standard FFP and photochemically-treated FFP in coagulopathic patients prior to invasive procedures
De Pietri 2016	Comparison of FFP transfusion guided by thromboelastography versus standard coagulation tests prior to invasive procedures. Fewer than 10% of included participants received central venous catheterisation
Etemadrezaie 2007	Comparison of FFP and saline in severe traumatic brain injury
Freeman 1998	Comparison of solvent/detergent FFP and standard FFP in orthotopic liver transplantation
Friedman 1989	Non-randomised, observational study
Gallieni 1995	Case-series
Harter 2004	Commentary
Holcomb 2015	Comparison of plasma:platelet: red blood cell ratios in severe trauma with massive haemorrhage
Mintz 2006	Comparison of photochemically-treated and standard FFP in patients with coagulopathy of liver disease
Napolitano 2012	Non-randomised, observational study
NCT00233246	Study withdrawn prior to enrolment
NCT00953901	Study withdrawn prior to enrolment
NCT01754545	Study withdrawn prior to enrolment; wrong subject group
Tinmouth 2008	Comparison of high and standard dose FFP in coagulopathic patients undergoing invasive procedures
Weigand 2009	Non-randomised, observational study
Williamson 1999	Comparison of solvent/detergent and standard FFP

FFP: fresh frozen plasma