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(A) Ptpn22-/- mice have mild neutrophilia. Bloods from 17 Ptpn22-/- and 22 matched control mice were labeled for CD11b and Ly6G and analysed by flow cytometry. Data (means ± SEM) were pooled from four separate experiments; **, p<0.01. (B) Cell surface L-selectin was analysed in unstimulated neutrophils from bloods of 8 wild-type and 7 Ptpn22-/- mice. Neutrophils were gated for analysis of CD62L staining; MFIs are plotted.
