Table 3. Relationships between modifiable lifestyle factors and arterial waveform parametersa.
Modifiable factor and level | Arterial waveform parameter | ||||||
---|---|---|---|---|---|---|---|
Brachial systolic blood pressure (mm Hg) | Aortic systolic blood pressure (mm Hg) | Augmentation index | Backward pressure amplitude (mm Hg) | Peak reservoir pressure (mm Hg) | loge(excess pressure integral (mm Hg s)) | Pulse wave velocity (m.s−1) | |
Heavy alcohol consumption | |||||||
Neverb | 139.3 (0.6) | 131.0 (0.6) | 30.4 (0.3) | 21.34 (0.18) | 121.6 (0.5) | 1.34 | 9.50 (0.02) |
≤1 per monthc | 1.7 (0.4, 2.9) | 1.6 (0.4, 2.9) | 0.5 (−0.2, 1.2) | 0.41 (0.0, 0.82) | 1.5 (0.4, 2.7) | (0.01) 0.02 (−0.01, 0.04) | 0.06 (0.01, 0.12) |
Weekly, daily or almost dailyc | 4.2 (1.9, 6.5) | 3.9 (1.6, 6.1) | 1.0 (−0.3, 2.2) | 0.34 (−0.39, 1.08) | 3.2 (1.1, 5.2) | 0.03 (−0.01, 0.08) | 0.14 (0.04, 0.23) |
P=0.0003 | P=0.0005 | P=0.19 | P=0.13 | P=0.0013 | P=0.19 | P=0.0046 | |
Smoking | |||||||
Non-smokerb | 139.1 (0.6) | 130.8 (0.6) | 29.9 (0.3) | 21.32 (0.20) | 121.6 (0.6) | 1.34 (0.01) | 9.50 (0.03) |
Ex-smokerc | 1.2 (0.1,2.3) | 1.3 (0.2,2.3) | 0.6 (0.0, 1.2) | 0.23 (−0.11, 0.58) 0.10 | 0.8 (−0.1,1.8) | 0.02 (−0.00, 0.04) | 0.05 (0.01,0.10) |
Current smokerc | 1.3 (−0.9, 3.5) | 1.1 (−1.0, 3.3) | 3.7 (2.5, 4.9) | (−0.61, 0.81) | 0.2 (−1.8, 2.2) | 0.04 (−0.01, 0.08) | −0.01 (−0.10, 0.08) |
P=0.07 | P=0.05 | P<0.0001 | P=0.42 | P=0.23 | P=0.08 | P=0.070 | |
Body mass index (kg.m−2) | 0.57 (0.46, 0.68) | 0.51 (0.40, 0.62) | −0.2 (−0.3, −0.2) | 0.03 (−0.01, 0.06) | 0.5 (0.4, 0.6) | 0.005 (0.002, 0.007) | 0.02 (0.01, 0.02) |
P<0.0001 | P<0.0001 | P<0.0001 | P=0.17 | P<0.0001 | P<0.0001 | P<0.0001 |
Adjusted for age, sex, ethnicity, antihypertensive use, diabetes and cardiovascular disease, plus pulse rate for augmentation index; P-values listed are for main effects.
Reference group—values are adjusted means (95% confidence intervals).
Values are differences (increments) in adjusted means (95% confidence intervals); *P<0.05, †P<0.01, ‡P<0.001 compared with reference group (for categorical variables) or for the slope (for BMI); 95% confidence intervals that do not encompass 0 and significant main effects (P<0.05) for waveform variables are in bold.