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. Author manuscript; available in PMC: 2017 May 22.
Published in final edited form as: Hypertension. 2017 Apr 17;69(6):1207–1216. doi: 10.1161/HYPERTENSIONAHA.117.09156

Figure 3. NPNT drives aldosterone production, likely through receptor ITGB1.

Figure 3

(a). NPNT overexpression increases protein-normalized aldosterone production, compared to vector control (n=4).

(b). NPNT silencing decreases protein-normalized aldosterone production, compared to non-targeting control (n=4).

(c). ITGB1 silencing decreases protein-normalized aldosterone production, compared to non-targeting control (n=4).

Bars represent mean expression per group±s.e.m. Statistical analyses were conducted by Student's t-test. *P<0.05; **P<0.005; ***P<0.0005