Skip to main content
. Author manuscript; available in PMC: 2018 Jan 12.
Published in final edited form as: Hypertension. 2017 May 15;70(1):192–200. doi: 10.1161/HYPERTENSIONAHA.116.08832

Figure 4. Changes in renal responses.

Figure 4

Change from baseline ± SEM in urinary sodium clearance (UNaV) (A), fractional excretion of sodium (FeNa) (B), free water clearance (FWC) (C) and urinary excretion of nitric oxide metabolites (UNOxV) (D) following treatment with placebo (blue line) and big ET-1 (red line). *p <0.05, **p <0.01 and ****p <0.0001 for placebo vs. big ET-1 (ANOVA plus Bonferroni correction for significance at specific time points).