Table 1. Differences in skin biochemical responses to placebo vs. slow sodium by sex.

Women have a lower skin K compared to men (p < 0.01 post placebo and slow sodium) and consequently have higher Na⁺:K⁺ ratio than men (p < 0.001 post placebo and salt).

Variable	Men (n=24)			Women (n=24)
	Placebo	Slow sodium	P-value	Placebo	Slow sodium	P-value
Skin Na+, mg/g	2.02±0.06	2.27±0.08	0.02	2.15±0.05	2.14±0.03	0.84
Skin K+, mg/g	0.80±0.03	0.82±0.04	0.59	0.68±0.03	0.65±0.02	0.28
Skin Na+:K+	2.59±0.09	2.88±0.12	0.008	3.23±0.10	3.36±0.12	0.31