Table 2. Differences in haemodynamic responses to placebo vs. slow sodium by sex.

Variable	Males (n=24)			Females (n=24)
	Placebo	Slow sodium	P-value	Placebo	Slow sodium	P-value
Body weight, kg	73.6±2.5	73.6±2.5	0.93	63.5±1.6	64.2±1.6	0.01
Office measurements
Seated SBP, mmHg	120±2	119±2	0.85	114±2	114±2	0.72
Seated DBP, mmHg	71±2	71±2	0.98	73±2	73±1	0.75
Seated MAP, mmHg	87±1	87±2	0.65	87±2	88±1	0.43
Seated HR, bpm	72±2	68±2	0.12	74±2	72±2	0.30
Supine SBP, mmHg	116±2	116±4	0.91	111±2	113±2	0.27
Supine DBP, mmHg	65±2	65±2	0.72	68±2	69±1	0.55
Supine MAP, mmHg	83±2	82±1	0.62	83±2	84±2	0.33
Supine HR, bpm	60±2	58±2	0.15	64±2	63±2	0.23
Ambulatory BP, mmHg
24-hr SBP	121±1	122±2	0.57	114±1	118±1	< 0.001
24-hr DBP	73±2	73±2	0.46	71±1	73±1	0.05
24-hr MAP	96±2	96±2	0.89	91±1	93 ± 1	< 0.001
Day SBP	124±1	125±2	0.32	118±1	121 ± 2	0.02
Day DBP	76±2	76±2	0.34	75±2	76 ± 2	0.33
Day MAP	98±2	98±2	0.93	95±1	97 ± 2	0.05
Night SBP	114±2	115±2	0.52	105±1	110 ± 1	< 0.001
Night DBP	65±2	66±2	0.65	63±1	65 ± 1	0.01
Night MAP	88±2	89±2	0.80	82±1	86 ± 1	< 0.001
Central haemodynamics
CSBP, mmHg	99±1	99±2	0.99	95±2	98±2	0.11
CDBP, mmHg	67±2	66±2	0.21	69±2	70±1	0.22
CMAP, mmHg	82±2	80±2	0.12	83±2	85±2	0.22
Augmentation index, %	4.5±2	4.5±2	0.98	13.7±3	14.5±3	0.58
PWV ms-1	5.2(4.7 – 5.6)	5.3(4.9 – 6.0)	0.10	5.0(4.7 – 5.5)	5.2(4.8 – 5.4)	0.93
Cardiac output, litres/min	6.6±0.3	7.0±0.4	0.08	5.6±0.3	5.8±0.3	0.10
Stroke volume, ml	107.9±5.2	116.8±6.5	0.09	86.0±4.0	88.9±3.6	0.29
PVR, dynes s-1 cm-5	1048±51	1045±64	0.57	1251±72	1212±66	0.46

Normally distributed data presented as mean±SEM. Non-normally distributed data are presented as median and IQR.