Table III. Association of IVF with maternal glucose concentrations and gestational diabetes mellitus, stratified by first-trimester body mass index.
Unadjusted | Adjusteda | |||||
---|---|---|---|---|---|---|
Under/normal weight (BMI < 25 kg/m2) (n = 661 versus 44) |
Overweight/obese (BMI ≥ 25 kg/m2) (n = 291 versus 26) |
Under/normal weight (BMI < 25 kg/m2) (n = 645 versus 39) |
Overweight/obese (BMI ≥ 25 kg/m2) (n = 285 versus 24) |
|||
ORb (95% CI) | OR (95% CI) | P-value | OR (95% CI) | P-value | ||
GDM | 1.44 (0.67–3.09) | 3.41 (1.51–7.71) | 1.14 (0.51–2.55) | 0.744 | 3.54 (1.44–8.72) | 0.006 |
Mean differenceb (95% CI) | Mean differenceb (95% CI) | Mean differenceb (95% CI) | ||||
Fasting glucose (mmol/L) | −0.01 (−0.10–0.13) | 0.36 (0.11–0.60) | −0.04 (−0.17 to 0.08) | 0.524 | 0.39 (0.13–0.65) | 0.003 |
OGTT 2-hour glucose (mmol/L) | 0.54 (0.12–0.97) | 1.10 (0.46–1.75) | 0.27 (−0.17 to 0.71) | 0.227 | 1.24 (0.56–1.91) | <0.001 |
OR, odds ratio; CI, confidence internal; OGTT, oral glucose tolerance test; GDM, gestational diabetes mellitus.
Adjusted for maternal age, ethnicity, family history of diabetes, previous history of GDM and delivery of macrosomic babies (>4 kg).
Reference to control group of women who conceived spontaneously in the respective BMI group.