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. Author manuscript; available in PMC: 2017 Nov 28.
Published in final edited form as: J Neurosci. 2017 Oct 12;37(46):11245–11254. doi: 10.1523/JNEUROSCI.1535-17.2017

Figure 1. Pax6, Neurog2, and Dmrt5 require Lhx2 for normal expression in the embryonic hippocampus.

Figure 1

A, B, EmxCre; Lhx2lox/lox brains at E15 display shrunken hippocampal primordia that express Zbtb20 and Prox1 (arrowheads), indicating that the hippocampus is specified. Pax6, Neurog2, and Dmrt5, normally expressed in the hippocampal ventricular zone (B, white asterisks), are greatly reduced upon loss of Lhx2 (A, black asterisks). Scale bar, 200 μm.