Table 1. In vivo results.

	Before Therapy	After Therapy	Variation* Before/After (%)	p
Shear Wave Imaging
Elastography (kPa)	76.1 ± 23.7	35.6 ± 7.2	- 52 ± 7	<0.001
Echocardiography
Doppler Mitral Valve (figure 5A)
- Maximal Velocity (m/s)	2.41 ± 0.50	1.73 ± 0.21	- 28 ± 6	0.007
- Maximal Pressure Gradient (mmHg)	24.0 ± 4.4	12.1 ± 1.4	- 49 ± 11	0.003
- Mean Velocity (m/s)	1.95 ± 0.36	1.38 ± 0.24	- 29 ± 6	0.001
- Mean Pressure Gradient (mmHg)	16.2 ± 3.2	8.2 ± 1.3	- 48 ± 7	<0.001
Mitral Valve Area (cm2)
- By pressure half time (PHT, fig 5B)	1.09 ± 0.09	1.57 ± 0.08	+ 143 ± 18	<0.001
- By continuity equation	1.10 ± 0.15	1.58 ± 0.15	+ 142 ± 15	<0.001
- By planimetry (fig 5C)	1.13 ± 0.13	1.54 ± 0.14	+ 137 ± 14	<0.001
Pulmonary artery pressure (mmHg)
- Maximal (Tricuspid Valve)	64.7 ± 12.8	34.1 ± 10.2	- 47 ± 12	<0.001
Cardiac Output# (L/min)	2.98 ± 0.1	2.96 ± 0.14	- 1 ± 0.2	0.83
Pressure Sensors (Millar) (mmHg)
Mean Diastolic Left Atrium pressure (LAP)	36.8 ± 6.2	20.2 ± 5.1	- 44 ± 11	0.004
Mean Diastolic Left Ventricle pressure (LVP)	17.4 ± 2.7	11.4 ± 1.9	- 35 ± 10	0.014
Mean Diastolic Gradient LVP-LAP	17.4 ± 2.4	8.8 ± 1.2	- 50 ± 13	0.002
Cardiac Flow Captor (L/min)
Swan-Ganz catheter	2.87 ± 0.11	2.96 ± 0.14	+ 3 ± 0.4	0.74

± SD

^*Variation Before/After = [(Result After – Result Before) / Result Before] x 100

^#Cardiac Output = HR x LVOT area x LVOT VTI