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Relationship between membrane potential and the open probability (Popen), the single Ca2+ channel current (i) and the whole-cell Ca2+ current (I; i.e. the product of N * Popen * i) (modified from (369)). Note the ∪-shaped current-voltage relationship for the whole-cell current. The whole-cell slope conductance (G=I/U) between 0 mV and +50 mV (where the Ca2+ channels are maximally active) is ~1 nS (i.e. 50 pA/50 mV).
