. Author manuscript; available in PMC: 2018 Dec 25.

Published in final edited form as: Mol Psychiatry. 2018 Jun 25:10.1038/s41380-018-0107-4. doi: 10.1038/s41380-018-0107-4

Table 1. Demographic and genotype data (mean ± SD).

	Healthy Controls	Alcohol Dependence	p-value (two-tailed)
Numbers	15	13
Age	42.8 (±10.2)	46.6 (±7.3)	0.281
IQ	115.6 (±9.9)	107.8 (+10.7)	0.090
Alcohol UK units/week	6.67 (±8.2)	0
Current Smokers	3	7
Cigarettes per day (current smokers)	10.0 (±5.0)	10.6 (±7.7)	0.247
Pack years (current and ex-smokers)	7.9 (±8.1)	23.6 (±14.5)	0.063
FTND (current smokers)	3.0 (±2.7)	3.7 (±3.1)	0.906
BDI on PET visit	0.2 (±0.6)	3.3 (±3.6)	0.004
STAI	30.3 (±7.4)	37.2 (±5.9)	0.012
SSAI (before PET 1)	27.9 (±6.6)	28.8 (±9.9)	0.797
UPPS-negative urgency	20.8 (±6.1)	27.4 (±4.1)	0.006
SADQ		38.5 (±11.2)
TRQ		18.9 (±5.1)
Alcohol Abstinence (days)	9.6 (±12.7)	604.6 (±866.5)	<0.001
OPRM1 G-allele carrier	2 of 11 (18.2%)	4 of 13 (30.1%)

Abbreviations: Fagerstrom Test for Nicotine Dependence (FTND), Beck Depression Inventory (BDI), Spielberger State and Trait Anxiety Inventory (SSAI, STAI), UPPS Impulsivity Scale (UPPS), Severity of Alcohol Dependence Questionnaire (SADQ), Time to Relapse Questionnaire (TRQ)