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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: J Immunol. 2018 Jun 6;201(2):714–724. doi: 10.4049/jimmunol.1700884

Figure 2. CXCL17 is unable to promote G protein-mediated signalling via isoforms of human GPR35.

Figure 2

Either the short, GPR35a, (A, B) or the N-terminally extended, GPR35b, (C) isoforms of human GPR35 were expressed in HEK293 cells along with the chimeric G protein α subunits Gq-G13 (A) or Gq-Gi1/2 (B, C). Following incubation with the indicated concentrations of zaprinast (filled circles), lodoxamide (filled triangles) or CXCL17 (open symbols) for 30 minutes levels of inositol phosphates were measured.