. Author manuscript; available in PMC: 2019 Jul 24.
Published in final edited form as: Genet Med. 2018 Sep 14;21(4):904–912. doi: 10.1038/s41436-018-0274-3
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms