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. Author manuscript; available in PMC: 2019 Feb 27.
Published in final edited form as: Eur J Heart Fail. 2018 Jun 3;20(10):1392–1400. doi: 10.1002/ejhf.1216

Table 2. Prescribed medical therapies at baseline based on age, sex and left ventricular ejection fraction.

All LVEF ≤40% LVEF >40%
Men (n=591) Women (n=290) P Men (n=322) Women (n=132) P Men (n=269) Women (n=158) P
Beta-blocker 433 (73.4) 209 (72.1) 0.69 266 (82.6) 100 (75.8) 0.12 167 (62.1) 109 (69.0) 0.17
ACE inhibitor 433 (73.3) 198 (68.3) 0.13 254 (78.9) 94 (71.2) 0.09 179 (66.5) 104 (65.8) 0.92
ARB 109 (18.5) 71 (24.5) 0.041 59 (18.3) 33 (25.0) 0.12 50 (18.6) 38 (24.1) 0.22
MRA 195 (33.0) 108 (37.4) 0.2 147 (45.7) 68 (51.5) 0.26 48 (36.4) 40 (25.3) 0.08
Loop diuretic 262 (44.3) 125 (43.1) 0.77 201 (62.4) 90 (68.2) 0.28 61 (22.7) 35 (22.2) 1.0
All LVEF ≤40% LVEF >40%
<60 (n=597) ≥60 (n=284) P <60 (n=295) ≥60 (n=159) P <60 (n=302) ≥60 (n=125) P
Beta-blocker 435 (72.9) 207 (73.1) 1.0 246 (83.4) 120 (75.5) 0.05 189 (62.6) 87 (69.6) 0.18
ACE inhibitor 429 (71.9) 202 (71.1) 0.87 225 (76.3) 123 (77.4) 0.82 204 (67.5) 79 (63.2) 0.43
ARB 113 (19.0) 67 (23.7) 0.11 63 (21.4) 29 (18.2) 0.46 50 (16.6) 38 (30.4) 0.002
MRA 208 (34.9) 95 (33.5) 0.7 153 (51.9) 62 (39.0) 0.01 55 (18.2) 33 (26.4) 0.07
Loop diuretic 233 (39.0) 154 (54.2) <0.0001 182 (61.7) 109 (68.6) 0.15 51 (16.9) 45 (36.0) 0.0001

(ACE – angiotensin converting enzyme, ARB – angiotensin II receptor blocker, MRA – mineralocorticoid antagonist)