Table 4. Univariable and multivariable analyses for the primary and secondary end-points.
HR for Women vs Men | All-Cause Mortality | Cardiovascular Death | Non-Sudden Death | Sudden death | ||||
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
Univariable | 0.64 (0.44, 0.94) | 0.020 | 0.58 (0.36, 0.93) | 0.025 | 0.68 (0.44, 1.05) | 0.088 | 0.58 (0.28, 1.21) | 0.15 |
Multivariable* | 0.61 (0.41, 0.92) | 0.018 | 0.60 (0.35, 1.05) | 0.074 | 0.63 (0.39, 1.02) | 0.060 | 0.70 (0.30, 1.63) | 0.41 |
HR based on Age (per 10 years increase) |
All-Cause Mortality | Cardiovascular Death | Non-Sudden Death | Sudden death | ||||
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
Univariable | 1.32 (1.17, 1.48) | <0.00001 | 1.12 (0.95, 1.31) | 0.18 | 1.51 (1.29, 1.78) | <0.00001 | 0.92 (0.73, 1.15) | 0.47 |
Multivariable† | 1.36 (1.20, 1.55) | <0.0001 | 1.16 (0.98, 1.37) | 0.078 | 1.51 (1.26, 1.82) | <0.00001 | 0.99 (0.78, 1.24) | 0.90 |
adjusted for left ventricular ejection fraction, New York Heart Association Class, atrial fibrillation, left bundle branch block, smoking, the presence of late gadolinium enhancement, age and the presence of an implantable cardioverter defibrillator or cardiac resynchronisation therapy as time varying co-variates
adjusted for left ventricular ejection fraction, New York Heart Association Class, atrial fibrillation, left bundle branch block, smoking, the presence of late gadolinium enhancement, sex and the presence of an implantable cardioverter defibrillator or cardiac resynchronisation therapy as time varying co-variates