Table 1. Wording of recommendations.

Recommendation	Language	Meaning for patients	Meaning for clinicians
Positive recommendation	The intervention or investigation is recommended	Most patients would want the intervention or investigation	Most patients should receive the intervention or investigation.
Negative recommendation	The intervention or investigation is not recommended.	Most patients would not want the intervention or investigation	Most patients should not receive the intervention or investigation.
Conditional recommendation	The intervention or investigation may be considered	Some patients would want the recommended intervention or investigation but others would not.	Different choices may be applicable to different patients depending on their values and preferences. The clinician should discuss the risks and benefits with the patient before reaching a decision
Insufficient evidence	The intervention or investigation is not recommended	Most patients would not want the intervention or investigation	Most patients should not receive the intervention or investigation.