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. Author manuscript; available in PMC: 2019 Mar 14.
Published in final edited form as: FEBS J. 2018 Oct 1;285(22):4165–4180. doi: 10.1111/febs.14660

Fig. 9.

Fig. 9

Binding of INI1/hSNF5 RPT1 and DNA to the MYC:MAX bHLHZip dimer are mutually exclusive. Top: overlay of 1H,15N HSQC spectra of RPT1 without (black) and with (red, ratio 1 : 1) unlabeled MYC:MAX bHLHZip dimer bound to DNA. Bottom: overlay 1H,15N BST TROSY spectra of 15N-labeled MYC:MAX bHLHZip dimer bound to DNA without (black) and with (red, ratio 1 : 1) unlabeled RPT1 INI1. In both spectra, no chemical shift changes are observed, illustrating that INI1 RPT1 does not bind to the MYC:MAX dimer when this is bound to E-box DNA.