Table 2.
Reference | Field strength (T) | Cohort size | Acquisition time (min) | Localisation method | Nominal voxel size (cm3) | Absolute reproducibility (%)a |
---|---|---|---|---|---|---|
This study | 7 | 10 | 28 | 3D-CSI | 1.5×1.5×2.5 = 5.6mL | 26 |
6½ | 3D-CSI | 2.5×1.5×2.5 = 9.4mL | 39 | |||
Bakermans et al, 201724 | 3 | 8 | 7 | Single voxel 3D ISIS | (8.0)3 = 512mL | 40 |
1D ISIS with 1D CSI | - | 43 | ||||
1D ISIS with 1D CSI | - | 44 | ||||
Tyler et al, 200915 | 3 | 20 | 30 | 3D CSI | 1.5×1.5×2.5 = 5.6mL | 53 |
Shivu et al, 201029 | 3 | 1b | 23 | 3D ISIS | 4.4×5.5×3.7 = 90mL | 31 |
Schaefer et al, 199230 | 1.5 | 7 | 7 | 1D CSI | - | 22 |
Lamb et al, 199625 | 1.5 | 16 | 10 | 3D ISIS | 6.0×7.0×7.0 = 294mL | 38 c |
15 | 1D CSI | - | - | |||
30 | 2D ISIS + 1D CSI | 1.0cm thick slices | 46 c |
Absolute reproducibility is calculated as (CR ÷ Mean PCr/ATP) × 100%
A single subject was scanned 8 times to assess reproducibility.
Absolute reproducibility was computed by extracting raw values from Figure 5 in ref. 25 using WebPlotDigitizer (https://apps.automeris.io/wpd/)