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. Author manuscript; available in PMC: 2019 Jul 9.
Published in final edited form as: ACS Appl Mater Interfaces. 2019 Jun 19;11(26):22932–22940. doi: 10.1021/acsami.9b04663

Figure 5.

Figure 5

Surface functionalization of hRNFs: (a) biotin-labeled hRNFs (Bio-hRNFs), (b) DBCO-labeled hRNFs (DBCO-hRNFs), and (c) avidin-coated hRNFs (Av-hRNFs). (i) SEM images of functional hRNFs, and (ii) TEM images and (iii) SIM images of QD-labeled functional hRNFs. The insets in the TEM images represent the magnified views of the selected region denoted as 1 and 2 in each particle. (d–f) Schematic illustration showing labeling of each functional hRNFs with surface-modified QDs through selective interactions. The functional hRNFs are labeled with QDs as follows: streptavidin-modified QDs (STV-QD605) for Bio-hRNFs, azide-modifed QDs (N3-QD525) for DBCO-hRNFs, and biotin-modified (Bio-QD575) for Av-hRNFs. Scale bars: 500 nm (SEM and TEM images), 50 nm (TEM insets), and 1 μm (SIM images).