. Author manuscript; available in PMC: 2020 Aug 11.

Published in final edited form as: Health Care Anal. 2020 Sep 1;28(3):193–227. doi: 10.1007/s10728-019-00381-x

Table 2. Key features of the multiple technology appraisal (MTA), single technology appraisal (STA) and fast-track appraisal (FTA) processes.

	Multiple technology appraisal (MTA) [42]	Single technology appraisal (STA) [39]	Fast track appraisal (FTA) [51]
Introduction	1999	2006	2017
Scope	Single or multiple technologies in one or more indications	Single technology in a single indication; usually new drugs or new indications of existing drugs	Single technologies where the ICER is expected to be < £10,000/QALY
Responsibility for assessment	Independent assessment group (AG)	Independent evidence review group (ERG)	ERG/NICE secretariat
Scope of assessment	AG produces an estimate of clinical and cost effectiveness, based on the manufacturer’s submission and a systematic review of the literature	ERG reviews manufacturer’s submission and prepares additional analysis as required	ERG/NICE prepares a commentary and technical judgements on the manufacturer’s submission
Output	Assessment report	ERG report	Joint technical briefing
Timeline	51 weeks	43 weeks	32 weeks