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. Author manuscript; available in PMC: 2020 Jan 31.
Published in final edited form as: Oncogene. 2019 Oct 4;39(5):975–986. doi: 10.1038/s41388-019-1042-9

Figure 2. NRARP can not only inhibit but also promote the proliferation of T-ALL cells.

Figure 2

(A) Effects of NRARP overexpression in T-ALL cell proliferation and (B) expansion. In (A) one of three independent assays (each performed in triplicate) is displayed whereas in (B) the fold change induced by NRARP is shown in comparison to control (Empty condition). (C) Effects of NRARP overexpression in T-ALL cell death as determined by annexinV staining and flow cytometry analysis. One of three independent assays performed in triplicate is displayed. (D) Effects of NRARP overexpression in cell cycle progression. Cells were sorted in G1 and cultured for 8h. n=3. (E) Analysis of the protein levels of the cell cycle regulator pRB. In (A), (B), (C) and (D) data represent the mean ± SEM. Statistical values were obtained using the Student’s t test. *p<0.05, **p<0.01, ***p<0.001.