Table 3. The genetic correlations among all pain phenotypes based on the UK Biobank.
Headache | Facial pain | Neck or shoulder pain | Stomach or abdominal pain | Back pain | Hip pain | Knee pain | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rg | P | rg | P | rg | P | rg | P | rg | P | rg | P | rg | P | |
Facial pain | 0.44 | 1.06 x 10-10 | ||||||||||||
Neck or shoulder pain | 0.61 | 1.39 x 10-94 | 0.52 | 3.27 x 10-10 | ||||||||||
Stomach or abdominal pain | 0.56 | 8.01 x 10-10 | 0.60 | 9.16 x 10-5 | 0.67 | 3.3 x 10-12 | ||||||||
Back pain | 0.53 | 2.79 x 10-36 | 0.47 | 4.50 x 10-7 | 0.83 | 2.11 x 10-100 | 0.56 | 5.61 x 10-6 | ||||||
Hip pain | 0.32 | 0.002 | 0.86 | 0.002 | 0.69 | 1.79 x 10-5 | 0.38 | 0.12 | 0.54 | 0.0004 | ||||
Knee pain | 0.39 | 3.70 x 10-13 | 0.33 | 0.01 | 0.53 | 1.53 x 10-14 | 0.53 | 0.0002 | 0.46 | 3.29 x 10-8 | 0.36 | 0.03 | ||
Pain all over body | 0.62 | 4.69 x 10-52 | 0.43 | 6.51 x 10-5 | 0.79 | 1.45 x 10-47 | 0.73 | 2.58 x 10-7 | 0.69 | 1.46 x 10-29 | 0.81 | 0.0004 | 0.36 | 5.56 x 10-5 |
P values < 0.001 (0.05/24+28) were considered as significant. Those significant rg values were in bold.
rg: genetic correlation