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(A) Synthetic scheme for the copolymerization of maleic anhydride with styrene to produce a perfectly alternating copolymer, followed by ring opening of the anhydride to produce a polyampholyte. (B) Synthetic scheme for the synthesis of a poly(DMAEMA-MAA) ampholyte, and a schematic showing how 50:50 monomer incorporation across all chains may not be evenly distributed within a single chain.
