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. Author manuscript; available in PMC: 2020 Jan 9.
Published in final edited form as: Circ Genom Precis Med. 2019 Nov 22;12(12):e002711. doi: 10.1161/CIRCGEN.119.002711

Figure 2. Univariable Mendelian randomization estimates (odds ratio with 95% CI per 1 SD increase in lipid fraction) for variants in specific gene regions.

Figure 2

Estimates are scaled to a unit SD increase in LDL-cholesterol for the HMGCR, PCSK9, and LDLR regions, and to a SD increase in triglycerides for the APOC3 and LPL regions.