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. Author manuscript; available in PMC: 2020 Mar 4.
Published in final edited form as: Brain Commun. 2019 Aug 6;1(1):fcz009. doi: 10.1093/braincomms/fcz009

Figure 2. Meta-analysis of 76 preclinical studies shows therapeutic potential for targeting mitochondrial pathways in ALS.

Figure 2

Forest plot showing the odds ratio and confidence intervals calculated from survival summary data from each study, weighted by study size. Overall effect estimate is demonstrated (with 95% confidence intervals) as a black diamond at the bottom of the graph. Heterogeneity is displayed as an I2 value. Results demonstrate an overall statistically significant effect favouring targeting of mitochondrial pathways in ALS.