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. Author manuscript; available in PMC: 2020 Jun 2.
Published in final edited form as: J Med Chem. 2020 May 6;63(10):5442–5457. doi: 10.1021/acs.jmedchem.0c00215

Figure 6.

Figure 6

Structural comparison of Ins(1,4,5)P3 (1), AdA and some of its truncated analogues including α-d-glucopyranosyl 1,3,4-trisphosphate (6) and β-d-glucopyranosyl 1,3,4-trisphosphate (7). The conserved regions of the structures involved in binding are drawn in blue while the differing auxiliary phosphate is shown in red.