Table 1. Associations with inflammatory arthritis development.

	All patients (n=357)	Arthritis (n=63)	No Arthritis (n=294)	HR* (95% CI)	P-value	HR† (95% CI)	P-value	HR‡ (95% CI)	P-value
MRI features
Feet (MTP 1-5)
Tenosynovitis, n (%)	29 (8)	17 (27)	12 (4)	6.64 (3.79; 1.63)	<0.001	4.75 (2.38; 9.49)	<0.001	3.14 (1.48; 6.64)	0.003
Synovitis, n (%)	34 (10)	16 (25)	18 (6)	4.46 (2.53; 0.88)	<0.001	2.48 (1.18; 5.23)	0.017	2.15 (0.98; 4.68)	0.06
BMO, n (%)	21 (6)	7 (11)	14 (5)	2.57 (1.17; 5.64)	0.019	0.66 (0.25; 1.69)	0.38	0.67 (0.25; 1.76)	0.41
Hands (MCP 2-5 and wrist)
Tenosynovitis, n (%)	95 (27)	41 (65)	54 (18)	6.59 (3.92; 11.08)	<0.001	6.16 (3.58; 10.62)	<0.001	5.36 (3.07; 9.37)	<0.001
Synovitis, n (%)	60 (17)	19 (30)	41 (14)	2.35 (1.37; 4.02)	0.002	1.06 (0.60; 1.87)	0.85	1.12 (0.63; 2.01)	0.69
BMO, n (%)	57 (16)	18 (29)	39 (13)	2.39 (1.39; 4.14)	0.002	1.94 (1.11; 3.38)	0.019	2.33 (1.31; 4.14)	0.004
Clinical features
Elevated CRP, n (%)	71 (21)	21 (33)	50 (18)	2.22 (1.31; 3.75)	0.003
ACPA and/or RF positive, n (%)	69 (21)	30 (48)	39 (14)	4.37 (2.65; 7.19)	<0.001

^*HR of univariable analyses.

^†HR of multivariable analyses including the three inflammatory MRI-features; multivariable analyses were performed for the MTP, MCP and wrist separately.

^‡Multivariable analyses including also CRP, positivity for ACPA and/or RF.