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. Author manuscript; available in PMC: 2021 Mar 2.
Published in final edited form as: Hum Mol Genet. 2020 Dec 18;29(20):3451–3463. doi: 10.1093/hmg/ddaa162

Figure 1.

Figure 1

Associations of metabolites with NASH-fibrosis variants in the Fenland and EPIC-Norfolk cohort. Metabolites are arranged by class and annotated whether they were obtained by untargeted or targeted methods. β ±standard error (SE) per allele from linear regression models are presented, adjusted for age, sex and the first ten genetic principal components and after standardization of each metabolite. Only metabolites significantly associated with at least one variant of interest (Q<0.05) are presented and marked in black. MG, monoglyceride; PC, phosphatidylcholine; PI, phosphatidylinositol; SM, sphingomyelin.