Skip to main content
. Author manuscript; available in PMC: 2019 Jun 20.
Published in final edited form as: Cochrane Database Syst Rev. 2018 Jun 20;6:CD007105. doi: 10.1002/14651858.CD007105.pub4

Comparison 2.

Local or regional anaesthesia for the prevention of persistent postoperative pain (classical analysis)

Outcome or subgroup title No. of
studies
No. of
participants
Statistical method Effect size

1 PPP after thoracotomy 6 Odds Ratio (M-H, Random, 95% CI) Subtotals only
  1.1 Three months follow-up 5 428 Odds Ratio (M-H, Random, 95% CI) 0.70 [0.40, 1.20]
  1.2 Six months follow-up 5 370 Odds Ratio (M-H, Random, 95% CI) 0.39 [0.24, 0.63]
2 PPP after cardiac surgery 2 Mean Difference (IV, Random, 95% CI) Subtotals only
  2.1 Three months follow-up 2 116 Mean Difference (IV, Random, 95% CI) −0.77 [−1.74, 0.20]
3 PPP after breast cancer surgery 19 Odds Ratio (M-H, Random, 95% CI) Subtotals only
  3.1 Three months follow-up 11 966 Odds Ratio (M-H, Random, 95% CI) 0.34 [0.19, 0.61]
  3.2 Six months follow-up 9 515 Odds Ratio (M-H, Random, 95% CI) 0.56 [0.37, 0.84]
  3.3 12 months follow-up 2 113 Odds Ratio (M-H, Random, 95% CI) 0.63 [0.04, 10.47]
4 PPP after caesarean section 4 Odds Ratio (M-H, Random, 95% CI) Subtotals only
  4.1 Three months follow-up 2 137 Odds Ratio (M-H, Random, 95% CI) 1.09 [0.39, 3.07]
  4.2 Six months follow-up 3 492 Odds Ratio (M-H, Random, 95% CI) 0.44 [0.26, 0.74]
5 PPP after amputation 2 Odds Ratio (M-H, Random, 95% CI) Totals not selected
6 PPP after laparotomy 2 Odds Ratio (M-H, Random, 95% CI) Totals not selected
7 PPP after hernia repair 2 Odds Ratio (M-H, Random, 95% CI) Totals not selected
8 PPP after hysterectomy 2 135 Mean Difference (IV, Random, 95% CI) 1.90 [−1.23, 5.02]
  8.1 Three months follow-up 2 135 Mean Difference (IV, Random, 95% CI) 1.90 [−1.23, 5.02]