. Author manuscript; available in PMC: 2019 Nov 15.

Published in final edited form as: J Neurochem. 2019 Mar 6;149(1):41–53. doi: 10.1111/jnc.14646

Table 3.

. Dissociation (k_off) rate constants of [³H]muscimol binding at +4 ºC in recombinant receptors expressed in HEK293 cells

Recombinant receptors	k_off (min⁻¹)
α1β2γ2	0.352 ± 0.009
α6β2γ2	0.086 ± 0.010^{*, }
α6β2δ	0.015 ± 0.003^***

Dissociation rate constants (k_off) of [³H]muscimol binding from recombinant receptors (n=3 independent transfections and independent experiments performed in triplicate technical replicates. The results are expressed as mean ± SEM values). Statistical comparison of recombinant receptor values:

^***

p<0.001, significantly different from the corresponding α1β2γ2 values;

^**

p<0.01, significantly different from the α6β2δ value (one-way ANOVA followed by Tukey’s post hoc test).