Figure 1. Exudates in Coats’ disease on (A) fundus photograph and (B) optical coherence tomography, OCT from a 7-year-old boy, and (C) low power and (D) high power histopathologic staining with hematoxylin and eosin (H&E) from an enucleated repository eye.

The vertical and horizontal white dotted lines on the photograph correspond to the main and inset OCT line scans respectively, while the black dotted box on the low-power micrograph denotes the area shown in the high-power micrograph. OCT shows that exudates are found both intraretinally (yellow arrows) and subretinally (yellow arrowhead). The inset OCT demonstrates the presence of a subretinal fluid pocket (blue arrow) that is difficult to visualize on a 2-dimensional photograph. On light micrographs, exudates appear as pinkish eosinophilic material in multiple intraretinal layers and subretinally (yellow arrows). The subretinal exudates are interspersed in subretinal fluid (blue arrows). Higher power magnification demonstrates the presence of pigment and lipid laden macrophages (black arrows) amongst exudates (yellow arrow) in the subretinal space.