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Main voxel-based SPM analysis comparing the PD freezers to the non-freezers demonstrated significant VAChT binding reductions in the left hippocampal region, bilateral prefrontal and bilateral anterior cinguli. Additional reductions were seen in the striatum, including right more than left caudate and accumbens nuclei and putamina, bilateral limbic archicortex, bilateral gyri recti, right LGN, and right mid-cingulate cortex regions.
