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. Author manuscript; available in PMC: 2019 Dec 9.
Published in final edited form as: Curr Mol Pharmacol. 2019;12(3):167–183. doi: 10.2174/1874467212666190304121131

Fig. 3.

Fig. 3.

Endogenous CBP and p300 expression in and the growth of wild type, CBP (+/−), and p300 (+/−) cells. 3T3 cells were generated from MEF cells that are heterozygous deficient for either CBP or p300. (a) Heterozygous CBP (+/−) MEFs express significantly less CBP than either wild type (WT) or p300 heterozygous p300 (+/−) cells as demonstrated by Western blot. Conversely, p300 (+/−) cells express considerably less p300 than the other two cell types. (b) p300 (+/−) 3T3 cells had a significantly steeper growth curve than either the WT or CBP (+/−) cells.