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. Author manuscript; available in PMC: 2019 Dec 17.
Published in final edited form as: Int J Cancer. 2019 Apr 8;146(3):617–626. doi: 10.1002/ijc.32268

Table 5:

The number of women who had each cotest result prior to one, two and three negative cotests, and the number and percentage of women diagnosed with CIN2+ by the prior cotest result

N CIN2+ (N) CIN2+ (%)
HPV result at test preceding one negative cotest
Cytology result at test preceding one negative cotest HPV
negative
. HPV
positive
Total HPV
negative
. HPV
positive
Total HPV
negative
. HPV
positive
Total
NILM 58166 22035 799 81000 33 19 5 57 0.057 0.086 0.626 0.070
. 1431 - 5 1436 2 - 0 2 0.140 0.000 0.139
ASCUS 274 106 372 752 0 0 2 2 0.000 0.000 0.538 0.266
LSIL 74 8 125 207 1 0 0 1 1.351 0.000 0.000 0.483
High grade 159 9 49 217 0 0 0 0 0.000 0.000 0.000 0.000
Total 60104 22158 1350 83612 36 19 7 62 0.060 0.086 0.519 0.074
ASCUS+ 507 123 546 1176 1 0 2 3 0.197 0.000 0.366 0.255
HPV result at test preceding two negative cotests
Cytology result at test preceding two negative cotests HPV
negative
. HPV
positive
Total HPV
negative
. HPV
positive
Total HPV
negative
. HPV
positive
Total
NILM 18858 9210 486 28554 9 2 1 12 0.048 0.022 0.206 0.042
. 597 - 12 609 1 0 1 0.168 0.000 0.164
ASCUS 925 121 75 1121 1 0 0 1 0.108 0.000 0.000 0.089
LSIL 35 11 16 62 0 0 0 0 0.000 0.000 0.000 0.000
High-grade 37 3 7 47 0 0 0 0 0.000 0.000 0.000 0.000
Total 20452 9345 596 30393 11 2 1 14 0.054 0.021 0.168 0.046
ASCUS+ 997 135 98 1230 1 0 0 1 0.100 0.000 0.000 0.081
HPV result at test preceding three negative cotests
Cytology result at test preceding three negative cotests HPV
negative
. HPV
positive
Total HPV
negative
. HPV
positive
Total HPV
negative
. HPV
positive
Total
NILM 2434 2011 69 4514 1 0 0 1 0.041 0.000 0.000 0.022
. 58 2 60 0 0 0 0.000 0.000 0.000
ASCUS 89 27 2 118 0 0 0 0 0.000 0.000 0.000 0.000
LSIL 3 1 1 5 0 0 0 0 0.000 0.000 0.000 0.000
High-grade 6 0 0 6 0 0 0 0 0.000 0.000
Total 2590 2039 74 4703 1 0 0 1 0.039 0.000 0.000 0.021
ASCUS+ 98 28 3 129 0 0 0 0 0.000 0.000 0.000 0.000

NILM: negative for intraepithelial lesions or malignancy, ASCUS: atypical squamous cells of undetermined significance, LSIL: low grade squamous intraepithelial lesion