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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Med Phys. 2019 Apr 1;46(5):2330–2336. doi: 10.1002/mp.13502

Figure 1.

Figure 1.

Overall framework of our proposed approach. Deformable image registration (DIR) was used to register end of exhalation (EE) CT to deep inspiration breath hold (DIBH) CT. The resultant deformation vector field (DVF) was then used to map the CT numbers from the EE CT to the DIBH CT space, resulting in deformed EE CT v1. At the same time, Jacobian was calculated from the DVF and used to correct the CT numbers inside the lung for the deformed EE CT v1, resulting in deformed EE CT v2, which improved the accuracy of the CT numbers.