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. Author manuscript; available in PMC: 2020 Jun 12.
Published in final edited form as: Hum Brain Mapp. 2019 Apr 1;40(10):3125–3138. doi: 10.1002/hbm.24585

Table 5.

Multiple Linear Regression Analyses of Anterior Frontal Lobe ROI’s Age-related change in D2-like receptor availability (BPND) using [18F]Fallypride PET in Study 2.

Model Parameter Anterior orbital gyrus Cingulate gyrus, anterior Inferior frontal gyrus Lateral orbital gyrus Middle frontal gyrus Superior frontal gyrus
N 129 130 128 125 124 121
Baseline R2 0.354*** 0.48*** 0.488*** 0.284*** 0.394*** 0.683***
Linear Age −0.0063
[ −0.0093,
−0.0034 ]
−0.0037
[ −0.0056,
−0.0018 ]
−0.0059
[ −0.0085,
−0.0033 ]
−0.0082
[ −0.011,
−0.005 ]
−0.0068
[ −0.0095,
−0.0042 ]
−0.0033
[ −0.0053,
−0.0013 ]
R2 change 0.079*** 0.052*** 0.071*** 0.122*** 0.109*** 0.027**
Quadratic Age −0.035
[ −0.053,
−0.018 ]
−0.014
[ −0.026,
−0.003 ]
−0.035
[ −0.05,
−0.02 ]
−0.038
[ −0.056,
−0.019 ]
−0.034
[ −0.049,
−0.019 ]
−0.023
[ −0.034,
−0.012 ]
Age2 0.00031
[ 0.00012, 0.00049 ]
0.00011
[ −5.9e−06,
0.00023 ]
0.00031
[ 0.00015, 0.00046 ]
0.00031
[ 0.00012,
5e-04 ]
0.00028
[ 0.00013, 0.00044 ]
0.00021
[ 8.9e−05, 0.00032 ]
R2 change 0.045** 0.013 0.049*** 0.046** 0.048*** 0.027***

Notes

Significant effects are denoted in bold.

Full regression tables can be found in the online application http://13.58.222.229:3838/agebp/.

*

p < .05.

**

p < .01.

***

p < .001.