Table 1.

Maternal, Delivery and Infant Characteristics by Infection Status

	No Infection (n= 2,108,156)	Any Infection (n= 29,856)
Maternal characteristics
Maternal age - mean (sd)	28.7 (5.3)	27.6 (5.6)
Maternal tobacco use** - n (%)	324,493 (15.4)	5,671 (19)
Maternal asthma - n (%)	4,844 (0.2)	158 (0.5)
Maternal seizures - n (%)	3,592 (0.2)	106 (0.4)
Maternal hypertension - n (%)	53,314 (2.5)	1,007 (3.4)
Maternal diabetes mellitus - n (%)	6,358 (0.3)	291 (1.0)
Maternal mental health diagnosis - n (%)	15,820 (0.75)	596 (2.0)
Delivery characteristics
Gestational age - mean (sd)	39.4 (1.9)	39 (2.4)
Prolonged labor - n (%)	27,456 (1.3)	493 (1.7)
Preterm premature rupture of membranes - n (%)	3,216 (0.2)	138 (0.5)
Antepartum hemorrhage - n (%)	35,748 (1.7)	1,045 (3.5)
Infant characteristics
Birthweight in grams – mean (sd)	3,508 (579)	3,415 (643)
Female sex - n (%)	1,024,770 (48.6)	14,474 (48.5)
Small for gestational age* - n (%)	66,785 (3.2)	1,201 (4.0)
Large for gestational age* - n (%)	67,774 (3.2)	1,057 (3.5)
Bronchopulmonary dysplasia or Respiratory Distress Syndrome - n (%)	5,666 (0.3)	171 (0.6)
Intraventricular hemorrhage - n (%)	5,666 (0.3)	171 (0.6)
Hyperbilirubinemia - n (%)	69,750 (3.3)	1,495 (5.0)
Fetal alcohol syndrome - n (%)	6,679 (0.3)	195 (0.7)
Outcomes
Bipolar disorder - n (%)	4,402 (0.2)	71 (0.2)
Psychosis, including schizophrenia - n (%)	4,307 (0.2)	75 (0.3)
Autism - n (%)	5,003 (0.2)	133 (0.5)
Depression - n (%)	20,749 (1.0)	409 (1.4)

The data show number (%) of pregnant women or infants by exposure status or mean (standard deviation) for maternal age, gestational age, and birthweight.

^*Numbers to indicate neonates that were either large or small for gestational age were estimated using the Marsal method.⁴⁹

^**Tobacco status is not known for women who gave birth before 1982.