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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Circ Genom Precis Med. 2019 Mar 21;12(4):e002471. doi: 10.1161/CIRCGEN.119.002471

Figure 1:

Figure 1:

Association between chromosome 9p21 and subsequent CHD events in all participants with baseline CHD (GENIUS-CHD) compared to association in CHD cases and CHD-free controls (CARDIoGRAMPlusC4D)

For the CARDIoGRAMPlusC4D meta-analysis estimate, 6 studies [LURIC, LIFE-Heart, GoDARTS, OHGS, PROSPER, WTCCC] were excluded as they were also included in GENIUS-CHD.

Estimates for GENIUS-CHD are also presented by subtype of CHD at baseline including acute coronary syndrome (ACS), stable coronary artery disease without prior MI (CAD/no MI) and Stable CAD with prior MI (CAD/MI). All estimates were adjusted for age and sex.