Table 3.
Relationship between participant demographics and understanding of purpose of research tumor profiling. Values within the table represent frequencies (row percentages).*
| Basic understanding (N=44) | Comprehensive understanding (N=41) | |||
|---|---|---|---|---|
| Characteristics of survey respondents | N (%) | P value | N (%) | P value |
| 30/44 (68%) | 24/44 (55%) | |||
| Age | 0.75 | 0.22 | ||
| ≥40 | 18 (72) | 16 (64) | ||
| <40 | 12 (63) | 8 (42) | ||
| Sex | 0.99 | 0.36 | ||
| Male | 12 (67) | 8 (44) | ||
| Female | 18 (69) | 16 (62) | ||
| Education | 0.05 | 0.01 | ||
| College graduate and higher | 21 (81) | 19 (73) | ||
| Less than college graduate | 9 (50) | 5 (28) | ||
| Race/ethnicity | 0.33 | 0.07 | ||
| White, non-Hispanic | 19 (76) | 17 (68) | ||
| Non-white or Hispanic | 11 (58) | 7 (37) | ||
| Experience with genetics and/or genetic testing | 0.32 | 0.34 | ||
| No | 8 (57) | 6 (43) | ||
| Yes | 22 (73) | 18 (60) | ||
| Genetic knowledge* | 0.03 | 0.01 | ||
| Low genetic knowledge | 6 (46) | 3 (23) | ||
| High genetic knowledge | 23 (82) | 20 (71) | ||
| Survey completed by | 0.29 | 0.08 | ||
| Parent/guardian | 24 (73) | 21 (64) | ||
| Patient | 6 (55) | 3 (27) | ||
| Characteristics of patients | ||||
| Participant-reported health status* | 0.99 | 0.99 | ||
| Excellent/very good | 17 (65) | 14 (54) | ||
| Good/fair/poor | 12 (71) | 9 (53) | ||
| Participant-reported likelihood of cure | 0.21 | 0.37 | ||
| ≥60% chance | 15 (60) | 12 (48) | ||
| <60% chance | 15 (79) | 12 (63) | ||
| Receiving treatment at time of survey completion | 0.05 | 0.23 | ||
| No | 19 (83) | 15 (65) | ||
| Yes | 11 (52) | 9 (43) | ||
| Received iCat treatment recommendation | 0.72 | 0.33 | ||
| No | 21 (66) | 19 (59) | ||
| Yes | 9 (75) | 5 (42) | ||
| Received targeted treatment | 0.99 | 0.99 | ||
| No | 29 (67) | 23 (53) | ||
| Yes | 1 (100) | 1 (100) | ||
| Respondent attitudes about iCat study | ||||
| Understanding of iCat information | 0.18 | 0.12 | ||
| Poor self-reported understanding | 14 (82) | 12 (71) | ||
| Good self-reported understanding | 16 (59) | 12 (44) | ||
| Helpfulness of participating in the study | 0.11 | 0.03 | ||
| Not helpful to myself/my child | 19 (79) | 17 (71) | ||
| Helpful | 11 (55) | 7 (35) | ||
*
Genetic knowledge was unknown for 3 participants and health status was unknown for 1 participant