Table A2.
Sensitivity analyses for the relationship between participant demographics and understanding of the purpose of research tumor profiling (“unsure” responses excluded). Values within the table represent frequencies (row percentages).*
| Basic understanding (N=33) | Comprehensive understanding (N=26) | |||
|---|---|---|---|---|
| Characteristics of survey respondents | N (%) | P value | N (%) | P value |
| 19/33 (58%) | 16/26 (62%) | |||
| Age | 0.27 | 0.99 | ||
| ≥40 | 14 (67) | 12 (63) | ||
| <40 | 5 (42) | 4 (57) | ||
| Sex | 0.72 | 0.66 | ||
| Male | 6 (50) | 4 (50) | ||
| Female | 13 (62) | 12 (67) | ||
| Education | 0.03 | 0.19 | ||
| College graduate and higher | 15 (75) | 13 (72) | ||
| Less than college graduate | 4 (31) | 3 (38) | ||
| Race/ethnicity | 0.30 | 0.42 | ||
| White, non-Hispanic | 12 (67) | 11 (69) | ||
| Non-white or Hispanic | 7 (47) | 5 (50) | ||
| Experience with genetics and/or genetic testing | 0.46 | 0.37 | ||
| No | 5 (45) | 3 (43) | ||
| Yes | 14 (64) | 13 (68) | ||
| Genetic knowledge* | 0.02 | 0.16 | ||
| Low genetic knowledge | 3 (30) | 2 (33) | ||
| High genetic knowledge | 16 (76) | 14 (70) | ||
| Survey completed by | 0.11 | 0.99 | ||
| Parent/guardian | 17 (65) | 14 (61) | ||
| Patient | 2 (29) | 2 (67) | ||
| Characteristics of patients | ||||
| Participant-reported health status | 1.00 | 0.42 | ||
| Excellent/very good | 11 (55) | 10 (56) | ||
| Good/fair/poor | 8 (62) | 6 (75) | ||
| Participant-reported likelihood of cure | 0.16 | 0.25 | ||
| ≥60% chance | 8 (44) | 7 (50) | ||
| <60% chance | 11 (73) | 9 (75) | ||
| Receiving treatment at time of survey completion | 0.29 | 0.23 | ||
| No | 10 (71) | 10 (77) | ||
| Yes | 9 (47) | 6 (46) | ||
| Received iCat treatment recommendation | 0.99 | 0.64 | ||
| No | 15 (58) | 13 (65) | ||
| Yes | 4 (57) | 3 (50) | ||
| Received targeted treatment | 0.99 | 0.99 | ||
| No | 18 (56) | 15 (60) | ||
| Yes | 1 (100) | 1 (100) | ||
| Respondent attitudes about iCat study | ||||
| Understanding of iCat information | 0.09 | 0.22 | ||
| Poor self-reported understanding | 10 (77) | 8 (80) | ||
| Good self-reported understanding | 9 (45) | 8 (50) | ||
| Helpfulness of participating in iCat study | 0.30 | 0.23 | ||
| Not helpful to myself/my child | 11 (69) | 10 (77) | ||
| Helpful | 8 (47) | 6 (46) | ||
*
For the analysis of “basic understanding,” genetic knowledge was unknown for 2 participants