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. Author manuscript; available in PMC: 2019 Jun 26.
Published in final edited form as: JAMA Pediatr. 2018 Jan 2;172(1):e174064. doi: 10.1001/jamapediatrics.2017.4064

Table 1.

Characteristics of 13,577 children enrolled in the PROBIT trial with outcome data at 16 years

N (%)
Characteristic Total (n = 13557) Intervention (n = 7064) Control (n = 6493)
Measured at child’s birth
Maternal age, y
 <20 1820 (13.4) 979 (13.9) 841 (13.0)
 20–34 11173 (82.4) 5792 (82.0) 5381 (82.9)
 ≥35 564 (4.2) 293 (4.1) 271 (4.2)
Maternal education
 Completed university 1842 (13.6) 1002 (14.2) 840 (12.9)
 Advanced secondary or partial university 6925 (51.1) 3365 (47.6) 3560 (54.8)
 Common secondary 4318 (31.9) 2406 (34.1) 1912 (29.4)
 Incomplete secondary 472 (3.5) 291 (4.1) 181 (2.8)
Paternal education
 Completed university 1737 (12.8) 936 (13.3) 801 (12.3)
 Advanced secondary or partial university 6205 (45.8) 2910 (41.2) 3295 (50.7)
 Common secondary 4883 (36.0) 2828 (40.0) 2055 (31.6)
 Incomplete secondary or unknown  732 (5.4) 390 (5.5) 342 (5.3)
Stratum-level variable
 East/Urban 4150 (30.6) 2215 (31.4) 1935 (29.8)
 East/Rural 2152 (15.9) 1075 (15.2) 1077 (16.6)
 West/Urban 3524 (26.0) 2296 (32.5) 1228 (18.9)
 West/Rural 3731 (27.5) 1478 (20.9) 2253 (34.7)
Number children in household
 0 7707 (56.8) 4152 (58.8) 3555 (54.8)
 1 4717 (34.8) 2365 (33.5) 2352 (36.2)
 2+ 1133 (8.4) 547 (7.7) 586 (9.0)
Maternal smoking during pregnancy
 No 13287 (98.0) 6898 (97.7) 6389 (98.4)
 Yes 270 (2.0) 166 (2.3) 104 (1.6)
Child sex
 Female 6576 (48.5) 3474 (49.2) 3102 (47.8)
 Male 6981 (51.5) 3590 (50.8) 3391 (52.2)
Birthweight, mean (SD), kg 3.44 (0.42) 3.44 (0.42) 3.44 (0.42)
Gestation length, mean (SD), wks 39.4 (1.0) 39.4 (1.0) 39.3 (1.0)
Measured in child’s first year
Duration of exclusive breastfeeding, mo
 <3 9861 (73.2) 3821 (54.7) 6040 (93.1)
 3–<6 3126 (23.2) 2727 (39.0) 399 (6.2)
 ≥6 484 (3.6) 437 (6.3) 47 (0.7)
Duration of any breastfeeding, mo
 <3 4692 (34.8) 2085 (29.8) 2607 (40.2)
 3–<6 3105 (23.0) 1590 (22.7) 1515 (23.4)
 ≥6 5676 (42.1) 3315 (47.4) 2361 (36.4)

SD = standard deviation