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. Author manuscript; available in PMC: 2019 Oct 7.
Published in final edited form as: J Neuroimaging. 2019 Jun 7;29(5):624–629. doi: 10.1111/jon.12642

Figure 2.

Figure 2.

Voxel location and representative 1H magnetic resonance spectra from a converter with MAPT mutation carrier

Posterior cingulate voxel is placed on a mid-sagittal 3D T1-weighted image (left). Example of 1H MRS for a converter with MAPT mutation at 2 years before symptom onset (A) and 2 year after symptom onset (B). The spectra are scaled to the creatine (Cr) peak as indicated with the dotted red line. During follow-up, the myoinositol (mI) peak is elevated from 2 years before symptom onset with mI/Cr ratio of 0.48 (A) to 2 years after symptom onset with mI/Cr ratio of 0.57 (B).