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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: JCO Precis Oncol. 2018 Apr 19;2:10.1200/PO.17.00198. doi: 10.1200/PO.17.00198

Fig 1.

Fig 1.

Case clinical information. (A) Preoperative magnetic resonance imaging (MRI). T2-weighted coronal sequence revealed a large, primarily hyperintense tumor that arises from the ventral aspect of the left tentorium, invaginating into the superior aspect of the cerebellum and causing diffuse edema therein. (B) Preoperative MRI. Tl-weighted axial sequence with gadolinium revealed strong enhancement. (C) Routine tumor histology. Hematoxylin and eosin (H&E)-stained representative section revealed a combination of epithelioid and spindled tumor cells among thick fibrous bands (× 200 magnification). (D) Routine tumor histology. Higher magnification depicts epithelioid tumor cells (eg, long arrow) and a mitotic figure (short arrow); many of the tumor cells exhibit somewhat vacuolated cytoplasm (H&E; × 400 magnification). (E-H) Tumor immunohistochemistry. Strong diffuse cytoplasmic immunostaining is exhibited for (E) desmin and (F) neuron-specific enolase (NSE). Diffuse membranous immunostaining is appreciated for (G) epithelial membrane antigen (EMA), and (H) CD99 (all photomicrographs taken at × 200 magnification).