Figure 1. hLPYK Structural Overview.
Model of hLPYK (PDB: 4IP7). Each monomer of the homotetramer is composed of three domains (A, B and C). The B domain interacts with the A domain of the same subunit. The A-A interface is formed between A domains from adjacent monomers. The C-C interface is formed by adjacent C domains. The allosteric sites are positioned along the C-C interface (shown in green for one monomer).