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. Author manuscript; available in PMC: 2020 Apr 21.
Published in final edited form as: J Leukoc Biol. 2019 Jul 16;106(5):1161–1176. doi: 10.1002/JLB.4A0419-123R

Figure 4. Comparative analysis of anti-RTA and anti-RTB MAbs in protecting KCs, J774E and LSECs from ricin toxin.

Figure 4.

Area under the curve (AUC) analysis of ricin-toxin neutralizing activities of a collection of MAbs targeting (A) RTA and (B) RTB. Cytotoxicity assays were performed across a range of MAb concentrations (starting at 20 μg/ml), as described in the Materials and Methods. AUC values and corresponding 95% confidence intervals were determined for each antibody from the results of ricin neutralization assays, with 4–13 biological replicates per concentration.