Table 1.
Subject information.
| Condition | ID# | Bank | Age | Sex | PMI (h) | AD pathology Tangles; Plaques | mBADLS |
|---|---|---|---|---|---|---|---|
| AD | 2006–38 | UCI | 56 | F | 3.9 | Stage 6; Stage C | 36 |
| AD | 2009–5 | UCI | 57 | F | 3.2 | Stage 6; Stage C | 39 |
| AD | 2010–25 | UCI | 57 | F | 3.2 | Stage 6; Stage C | 11 |
| AD | 2006–19 | UCI | 59 | M | 3.3 | Stage 6; Stage C | 14 |
| AD | 2006–36 | UCI | 61 | M | 5.6 | Stage 6; Stage C | 37 |
| DS | 2007–31 | UCI | 52 | F | 4.4 | Stage 6; Stage C | 21 |
| DS | 2005–7 | UCI | 54 | M | 4.5 | Stage 6; Stage C | 40 |
| DS | 2008–42 | UCI | 55 | M | 4.5 | Stage 6; Stage C | 42 |
| DS | 2008–8 | UCI | 57 | F | 5.3 | Stage 6; Stage C | 29 |
| DS | 2004–23 | UCI | 58 | M | 3.4 | Stage 6; Stage C | 42 |
| DS | 2010–31 | UCI | 62 | F | 2.4 | Stage 6; Stage C | 25 |
| Control | 1503 | U. Maryland | 53 | F | 5 | ||
| Control | 5117 | U. Maryland | 56 | M | 5 | ||
| Control | 4263 | U. Maryland | 61 | M | 6 | ||
| Control | 5326 | U. Maryland | 62 | M | 6 | ||
| Control | M3983M | U. Maryland | 52 | M | 2 | ||
| Control | Hsb3371 | VA WLAHC | 52 | M | 16 | ||
| Control | Hsb3529 | VA WLAHC | 58 | M | 9 | ||
| Control | Hsb3558 | VA WLAHC | 59 | F | 19.5 | ||
| Control | Hsb3589 | VA WLAHC | 53 | M | 15 | ||
| Control | Hsb3611 | VA WLAHC | 64 | M | 17.5 |
Age, sex, and postmortem interval (PMI) for all cases in the study. DS and AD cases had AD pathology with stage 6 tangles and stage C plaques. Modified Bristol Activities of Daily Living Scale (mBADLS) scores are shown (higher scores indicate greater functional dependency; 0–42 points scale). See Materials and Methods for details.