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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Cell Mol Med. 2008 Dec;12(6A):2165–2180. doi: 10.1111/j.1582-4934.2008.00552.x

Figure 6. Cytoskeletal remodeling at focal adhesions and regulation of smooth muscle contraction.

Figure 6

Integrins connect the extracellular matrix to actin filaments within the cell. Actin filaments are linked to cytoplasmic domain of integrin by linker proteins (green). Mechanical and/or contractile stimuli induce the cytoskeletal remodeling by recruiting signaling proteins (orange) to focal adhesions.