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. Author manuscript; available in PMC: 2020 Feb 13.
Published in final edited form as: J Neurochem. 2019 Nov 4;152(2):235–251. doi: 10.1111/jnc.14898

Figure 7.

Figure 7.

Data analysis of all assay results of the caudate and putamen of the AD cases chosen for BACE1 mRNA analysis (n=10) and age-matched controls (n=10). A: Oxidative damage of nucleic acid in the caudate and putamen from 10 AD cases and age-matched controls. A p value of < 0.05 was considered significant: *indicates p < 0.05 and ** indicates p < 0.01, vs. the controls. B: Biological consequence of oxidative damage to dopamine system in the caudate and putamen from 10 AD cases and age-matched controls. A p value of < 0.05 was considered significant, *indicates p < 0.05 vs. the controls. C: Density of VMAT2 and DNA oxidative adducts levels (rs = −0.678, p = 0.015), density of VMAT2 and RNA oxidative adducts levels (rs = −0.717, p = 0.030), as well as density of D1R and RNA oxidative adducts levels (rs = −0.750, p = 0.020) in the caudate from 10 AD cases. rs, the Spearman’s rank correlation coefficient.